Both lead to hormonal disorders 

Researches have proved that playing violent games increases cortisol significantly during playing and its level remains constant after playing. In males, gutkha is known to lead to decreased testosterone while in females it can cause impairment of ovarian morphology and function, oocyte quality, hormonal perturbations, foetal development and long-term health effects on the foetus. 
Ref: Toxicity of Gutkha, a Smokeless Tobacco Product Gone Global: Is There More to the Toxicity than Nicotine? – PMC (nih.gov) 
Ref: Toxic effects of smokeless tobacco on female reproductive health: A review – PMC (nih.gov) 

Both lead to family quarrels 

Often one reads reports wherein there is family violence and in some cases, even kids committing suicide when parents scold them for playing online games. This phenomenon also resonates with the quarrels in a family due to tobacco consumption  

Both give a false sense of strength/high/accomplishment 

Gutkha is known to be a stimulant and a relaxant wherein the addict gets on a short-term high and a perceived boost of energy. Online games are also designed to give a false sense of accomplishment through various means like level-ups or streaks or unlocking extra powers. But in reality, the player remains what he/she is, if not worse. 

Both make you socially alienated 

Studies have shown that generally, there was a significant difference between the social skills of students addicted to computer games and normal students. Normal students had a higher level of social skills in comparison with students addicted to computer games.  

On a similar note, tobacco is also associated with larger reductions in social contact, increases in social disengagement, and increases in loneliness over time.
Ref: Comparing the Social Skills of Students Addicted to Computer Games with Normal Students – PMC (nih.gov) 
Ref: New findings suggest smoking increases social isolation and loneliness | Imperial News | Imperial College London 

Both lead to a loss of productivity 

It is an established fact that gaming is a big drain on productive time as there is no meaningful outcome from the time a user spends playing games. Similarly, tobacco usage and addiction lead to higher absenteeism and work productivity loss. 

Both Expedite Ageing 

Excessive sitting has a direct correlation with the manifestation of multiple chronic ailments and gaming just makes you sit, in one place for long periods. Nothing more needs to be said about Gutkha’s impact on one’s life and health 

Both lead to emotional weakness 

Researches have found a negative correlation between problematic video gaming and psychological functioning concerning psychological symptoms, affectivity, coping, and self-esteem. One often sees withdrawal symptoms in addicted gamers like irritability, anxiety, or sadness. Gutkha is no different.
Ref: The withdrawal-related affective, gaming urge, and anhedonia symptoms of internet gaming disorder during abstinence – PMC (nih.gov) 

Both seem ’cool’ until the effects show up !